By: Patrick Glancy
Introduction
Many people suffering from depression have been told by their doctors that they have a genetic disease and they will never be cured. The doctors claiming this may not be helping their patient as much as they believe. There are differing opinions and theories on the cause of depression. There are arguments for the cause being biological, cognitive, and both. The perspective of this paper is that while biological factors have an influence on depression, depression is precipitated by stressful life events. The behavioral perspective a person holds of themselves, and their world, has an undeniable connection with how a stressful event will affect the person.
Cognitive Building Blocks of Depression
According to Ulrich (2008), low self-esteem is a risk factor for depression. Meaning a dysfunctional belief can make a person more vulnerable to depression. This information can be combined with the findings of Beeney (2008), in that self-esteem can allow for a negative memory bias which further increases vulnerability to depression.
As an example, a person with low self-esteem, which perpetuates a negative memory bias, will react to losing their job with a higher stress reaction than someone without these two contributing factors. When this combination is exposed to a particular stressful life event, it can result in symptoms of depression.
Life Perspective and Depression
A stressful life event which precipitates depression in one person does not need to hold the same level of stress to others exposed to the same event. According to Drevets (2009), exposure to stressful events through one’s life can combine. When exposed to a current stressful event, a person can have a stress reaction that is stronger than the current situation deserves because of previous exposure to similar events. Therefore, the root cause of stress may not be the more recent event, it may be earlier events. When this information is taken into consideration, it helps explain why the cognitive cause of depression is not always immediately clear. A person’s perception of their memories, perception of themselves, and re-exposure to events are different pieces to the puzzle of depression.
The Biological Aspect of Depression
Beck states in “The Evolution of the Cognitive Model of Depression and It’s Neurobiological Correlates” (Beck, Aaron T. 2008), that the cognitive model of depression is well founded and proven. But, this does not negate the clear effect that biological factors can have on depression. While it is evident that dysfunctional attitudes and beliefs can generate symptoms of depression, some biological functions, such as an overactive amygdala, facilitate formation of these dysfunctions by revivifying negative memory and emotions more readily.
Biology Interacting with Behaviors
A person can be biologically more susceptible to the building blocks of depression, and biology can be seen in the symptoms of depression. The cause of depression comes from the inner beliefs we hold of ourselves, our world, and the resulting skewed perception of our experiences. As an example, abandonment at a young age can create a profound sense of low self-worth that will affect how the person interacts with loved ones. People suffering from Borderline Personality Disorder tend to have traumatic childhoods, including abandonment.
There are arguments for biology being the cause of depression. There is research showing genes and brain chemistry that are unique to depression being found in individuals who have had depression. There is no apparent research where this particular biology exists prior to the onset of depression when no corresponding cognitive cause is present. Therefore these biological signs are found after the depression already exists.
Summary and Conclusion
Biology can be shown to be associated with depression. Biology can be shown to be a symptom of depression. But, biology cannot be shown to be a cause of depression. Depression can consistently be linked to past events in the patient’s life supporting the argument for cognitive cause. Additionally, many people with depression are able to have spontaneous remission of symptoms without psychological treatment (Andrews, 2001). This would not tend to be the case if their cause of depression were a result of their biological makeup.
The conclusion of this paper is that biology is limited to being associated with the cognitive cause of depression as well as assisting in the ease of onset of depression. Further research in this direction will lead to reliable techniques allowing depression sufferers to find relief.
References
Andrews, Gavin (2001) Placebo response in depression: bane of research, boon to therapy BJP March 2001 178:192-194; doi:10.1192/bjp.178.3.192
Beck, A. T. (2008). The evolution of the cognitive model of depression and its neurobiological correlates. The American Journal of Psychiatry, 165(8), 969-977. doi:10.1176/appi.ajp.2008.08050721
Beeney, J., & Arnett, P. A. (2008). Stress and memory bias interact to predict depression in multiple sclerosis. Neuropsychology, 22(1), 118-126. doi:10.1037/0894-4105.22.1.118
Drevets, W. (2009). The Diathesis-Stress Model. In Genes to Cognition Online. Retrieved from
www g2conline.org/2077
Orth, U., Robins, R. W., & Roberts, B. W. (2008). Low self-esteem prospectively predicts depression in adolescence and young adulthood. Journal of Personality and Social Psychology, 95(3), 695-708. doi:10.1037/0022-3514.95.3.695